2-CHLORO-6-METHOXYPYRIDINE-4-CARBONYL CH
2-Chloro-6-methoxyisonicotinoyl chloride
CAS: 116853-97-5
Molecular Formula: C7H5Cl2NO2
2-CHLORO-6-METHOXYPYRIDINE-4-CARBONYL CH - Names and Identifiers
2-CHLORO-6-METHOXYPYRIDINE-4-CARBONYL CH - Physico-chemical Properties
| Molecular Formula | C7H5Cl2NO2 |
| Molar Mass | 206.03 |
| Melting Point | 60°C |
| Boling Point | 60°C 0,07mm |
| Flash Point | 79°C/0.2mm |
| Storage Condition | Inert atmosphere,Room Temperature |
| Sensitive | Moisture Sensitive |
| Refractive Index | 1.5560 |
2-CHLORO-6-METHOXYPYRIDINE-4-CARBONYL CH - Risk and Safety
| Risk Codes | R34 - Causes burns R36 - Irritating to the eyes |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | 3265 |
| Hazard Note | Corrosive |
| Hazard Class | 8 |
| Packing Group | II |
2-CHLORO-6-METHOXYPYRIDINE-4-CARBONYL CH - Reference Information
| Application | 2-chloro-6-methoxyisonicotinoyl chloride can be used as an intermediate in pharmaceutical synthesis. It is prepared by the reaction of 2-chloro-6-methoxypyridine-4-carboxylic acid and thionyl chloride, it can be used to prepare the compound 2-chloro-6-methoxypyridine-4-carboxylic acid tert-butyl ester. |
| preparation | 2-chloro -6-methoxyisonicinoyl chloride is prepared as follows: 2-chloro -6-methoxypyridine -4-carboxylic acid (3.96g) is added to thionyl chloride (40ml), and heated and refluxed for 2 hours. Vacuum evaporates excess thionyl chloride, and evaporates the residue twice with dichloromethane to obtain 2-chloro-6-methoxyisonicotinoyl chloride, which is an almost colorless oil (4.17g). |
Last Update：2024-04-10 22:29:15
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View History
2-CHLORO-6-METHOXYPYRIDINE-4-CARBONYL CH
5-硝基-2-哌啶苯甲醛
(R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzoic acid
2-氨基-3-(2-苯甲酰氯)-5-乙基噻吩
N-(4-氨基丁基)丁烷-1,3-二胺
Methyl 3-methoxy-9,10-dihydrophenanthrene-2-carboxylate
2-phenylethylbenzoate
D 2439
Poly-L-arginine hydrochloride
2-甲硫基苯并噻唑
5-硝基-2-哌啶苯甲醛
(R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzoic acid
2-氨基-3-(2-苯甲酰氯)-5-乙基噻吩
N-(4-氨基丁基)丁烷-1,3-二胺
Methyl 3-methoxy-9,10-dihydrophenanthrene-2-carboxylate
2-phenylethylbenzoate
D 2439
Poly-L-arginine hydrochloride
2-甲硫基苯并噻唑